Other Pathology Nodes

To support molecular pathology, the MRC and EPSRC have also supported other five nodes led by the universities of Edinburgh, Glasgow, Manchester, Newcastle and Nottingham. Each node brings researchers, clinicians and industry together to develop molecular diagnostic tools, to enable stratification in different disease areas.

Edinburgh-St Andrews Consortium for Molecular Pathology, Informatics and Genome Sciences

The Edinburgh-St Andrews Consortium will bring molecular diagnostics into mainstream medicine by use of modern genome technologies and information across a range of diseases. The consortium will integrate state-of-the-art genomic and epigenomic methods for diagnosis of acutely ill children and will develop ‘liquid biopsies’ for managing cancer through analysis of circulating tumour DNA.

Manchester Molecular Pathology Innovation Centre

Developing biomarker based molecular pathology tests will be a major focus of the Manchester node with the initial work aimed at creating tests to diagnose, pick the right treatment and asses the response to treatment for a range of inflammatory conditions including rheumatoid arthritis, lupus and psoriasi.

Glasgow Molecular Pathology (GMP) Node

The Glasgow Molecular Pathology Node will integrate pathology, genomics and informatics. It will be located at the Queen Elizabeth University Hospital campus where the University of Glasgow has already established a world-leading reputation in precision medicine, including the £20 million Stratified Medicine Scotland Innovation Centre, £32 million Imaging Centre of Excellence, and £30 million Queen Elizabeth Teaching and Learning Centre including incubators for industry.

The Newcastle Proximity Laboratory

The Newcastle node will focus on developing new lab tests for rare and chronic diseases and will also be involved in training the next generation of molecular pathologists who will be vital in the delivery of precision medicine.

Nottingham Molecular Pathology Node (NMPN) for Integrated Multi-platform Biomarker Research and Knowledge Transfer

The Nottingham node will bring together informatics, computational modelling and molecular pathology to find new biomarkers for a range of diseases – particularly those affecting the digestive and respiratory systems and the liver. These new markers will help doctors pick the best treatments for their patients.